Skin and Bone Tumors Induced by Repeated Beta-Irradiation of Mice: Threshold Effect and p53 Mutations.
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چکیده
منابع مشابه
Low incidence of p53 mutations in UVA (365-nm)-induced skin tumors in hairless mice.
Mutations with clear "UVB fingerprints" have been observed in the p53 gene of human nonmelanoma skin tumors and of experimentally UVB-induced murine skin tumors. Although UVA (315-400 nm) radiation is also a complete carcinogen, its contribution to sunlight-induced mutagenesis remains poorly characterized. There is experimental evidence that the production of reactive oxygen species plays a mor...
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Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice.
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 1996
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.37.151